Instant relief for menopause symptoms
Instant relief
for menopause symptoms
Personalized hormone therapy to ease
Hot flashes
Low energy
Hair loss
Mood swings
Low libido
Adult acne
feel like you again in just 2 weeks* for $140/month
Precision Health Solution
Bioidentical Hormone Therapy
Testing 1 Million+ Biomarkers
Leading US Based Physicians
Personalized Progress Tracking
24/7 Online Support
“Biomarkers hold the key to truly personalized healthcare—understanding them transforms how we approach wellness and aging”
Backed by Dr. Mike Snyder, a world leader in precision medicine and cell genomics from Stanford University.
Hormone changes are real, and we’re here to listen.
Struggling with these symptoms?
Finally, care that adapts to you.
Own your health with an HRT plan that evolves with your body’s needs.
Dashboard
An easy-to-use dashboard that keeps you on track. See how your medications are working, check upcoming lab tests, and know when prescriptions are ready.
Precision Insights, Real Answers
We analyze 1 million biomarkers to create a plan tailored to you.
Access to All Your Data
View your results and track progress as your treatment evolves.
Prescription Meds Included
No additional cost for meds delivered to your door—100% personalized to you.
How we’ve transformed our patients
Get Started
The value of a doctor who believes in you
Your body is unique, and your menopause care should change with it to give you the best results possible.
Testing depth
1 million+
biomarkers
Testing depth
100
biomarkers
Testing depth
24
biomarkers
Hormones tested
9
estrogens
8
androgens
2
progesterones
8
adrenal hormones
Hormones tested
9
estrogens
8
androgens
2
progesterones
8
adrenal hormones
Hormones tested
1
estrogens
1
androgens
1
progesterones
0
adrenal hormones
Risk screening before test
Yes
Risk screening before test
Yes
Risk screening before test
No
Personalized dosing?
Personalized dosing?
Personalized dosing?
Prescribes testosterone?
Prescribes testosterone?
Prescribes testosterone?
Diagnostics included
Diagnostics included
Diagnostics included
Medicine included
Medicine included
Medicine included
Unlimited access to doctor
Unlimited access to doctor
Unlimited access to doctor
Fully personalized
Yes
Targeted medicine, precision health
Fully personalized
Yes
Fully personalized
No
Protocol evolves as you evolve
Monthly
Protocol evolves as you evolve
Annually
Protocol evolves as you evolve
No
Pricing
2k
/year
Pricing
$10k-$150k
/year
Pricing
$3k-$10k
/year
Concierge docs
Telehealth
Testing depth
1 million+
biomarkers
Testing depth
100
biomarkers
Testing depth
24
biomarkers
Hormones tested
9
estrogens
8
androgens
2
progesterones
8
adrenal hormones
Hormones tested
9
estrogens
8
androgens
2
progesterones
8
adrenal hormones
Hormones tested
1
estrogens
1
androgens
1
progesterones
0
adrenal hormones
Risk screening before test
Yes
Risk screening before treatment
Yes
Risk screening before treatment
No
Personalized dosing?
Personalized dosing?
Personalized dosing?
Prescribes testosterone?
Prescribes Testosterone?
Prescribes Testosterone?
Diagnostics included
Diagnostics included
Diagnostics included
Medicine included
Diagnostics included
Diagnostics included
Unlimited access to doctor
Diagnostics included
Diagnostics included
Fully personalized
Yes
Targeted medicine, precision health
Fully personalized
Yes
Fully personalized
No
Protocol evolves as you evolve
Monthly
Protocol evolves as you evolve
Annually
Protocol evolves as you evolve
No
Pricing
$2k
/year
Pricing
$10k-$150k
/year
Pricing
$3k-$10k
/year
HOW TO GET STARTED
Easy, online and effective.
Start feeling better after just 2 weeks.
A year of care built and evolving just for you.
You’re not alone in menopause. Here’s how our support and medical protocols evolve over a whole year to keep you feeling your best.
Genetic test
Blood test
Concierge
Consult
1 WEEK
Blood test
Dutch test
3 MONTHS
Blood test
Dutch test
7 MONTHS
PHASE 1
Analyze
Using the deepest diagnostic approach on the marker, we first understand how your biological pathways produce, process and react to hormones.
PHASE 2
Prep
After addressing some root causes of your hormonal imbalance, a Dutch test can get us a reliable picture of your true hormonal state. We’re making sure to not just throw hormones at a body that can’t effectively process them.
PHASE 3
Balance
Having tackled your unique root causes, we’re finally ready to move to a bespoke hormone formula-100% customized to your body’s unique needs. Monitoring how you evolve and feel allows us to adjust protocol at any time.
PHASE 4
Thrive
You’re now thriving for the long term. But bodies and lifestyles change all the time, and our care evolves with your needs. We re-test every 6 months and adjust your prescription and plan if needed.
Genetic test
Blood test
PHASE 1
Analyze
Using the deepest diagnostic approach on the marker, we first understand how your biological pathways produce, process and react to hormones.
Concierge
Consult
1 WEEK
PHASE 2
Prep
After addressing some root causes of your hormonal imbalance, a Dutch test can get us a reliable picture of your true hormonal state. We’re making sure to not just throw hormones at a body that can’t effectively process them.
Blood test
Dutch test
3 MONTHS
PHASE 3
Balance
Having tackled your unique root causes, we’re finally ready to move to a bespoke hormone formula-100% customized to your body’s unique needs. Monitoring how you evolve and feel allows us to adjust protocol at any time.
Blood test
Dutch test
7 MONTHS
PHASE 4
Thrive
You’re now thriving for the long term. But bodies and lifestyles change all the time, and our care evolves with your needs. We re-test every 6 months and adjust your prescription and plan if needed.
What you deserved to know about HRT all along
Reduction in hot flashes and night sweats within weeks of starting HRT.
Experience depression during menopause and find relief with HRT.
Reported improved hair and dental health after six months of HRT.
Reported improvement in memory and cognitive clarity within 6 months on HRT.
Women in our program experience better...
Transparent, simple pricing for extensive care
Joyful HRT Program
Annually
$3,000
$2,000
Save 33% once you sign up for the whole year
Billed annually
Save 33% once you sign up for the whole year. Billed annually
Monthly
$250
$140
EXCLUSIVE OFFER: Get 44% off your first month Billed monthly $250 after
EXCLUSIVE OFFER: Get 44% off your first month Billed monthly $250 after
No hidden fees, no insurance required
Cancel anytime
100% money-back guarantee
Full refund if you’re not qualified
Free shipping
24/7 access to doctor support
How does testing 1 million+ biomarkers help me?
Dr. Mike Snyder, a world leader in precision medicine from Stanford Medicine, shows how advanced biomarker testing leads to better, more personalized care.
Unlike most treatments that test just one type of estrogen, Joyful measures multiple forms to understand its full impact on your body.
Inspired by Dr. Snyder’s research, Joyful designs treatments tailored to your hormonal needs—delivering precise, effective care.
Significance of Biomarker Testing in Precision Medicine: Why biology is catalyzing breakthroughs in women’s health. Snyder’s biological aging patterns study: ‘Ageotypes’ provide window into how individuals age, Stanford study reports. Novel blood analysis method to measure thousand of molecules from a single drop of blood: ‘Theranos that works’: Stanford researchers say they’ve measured thousands of molecules from a single drop of blood.
Unlocking the science behind feeling like yourself again
Precision health starts with understanding you. Endophenotyping is a detailed analysis of genetic, cellular, and metabolic markers, to uncover what’s happening inside your body.
Going deeper than symptoms
Going deeper than symptoms
Most test stop at surface-level symptoms. Endophenotyping digs deeper and gives us insight to:
Your genetics and how they affect you
How hormones interact in your body
Specific markers that point to imbalances
How your cells are working
Brain and nerve responses
Metabolism and energy use
Gut health and environment
How well your organs are functioning
Testing that finds answers
Testing that finds answers
We find the root causes behind your symptoms to guide better, more precise care:
Genetic analysis
Hormone testing
Metabolism checks
Brain and nerve assessments
Gut and environmental health
Care that’s built for you
Care that’s built for you
This is the new way forward. Endophenotyping replaces one-size-fits-all care with solutions made for you. It’s healthcare that listens, understands and works for your body.
A $40,000 treatment for only $250 per month
We’ve made advanced healthcare simple and affordable. By using in-depth lab tests and cutting-edge technology, we lower costs without losing quality. Better care, made easy and accessible for women.
4x top 1% concierge doctor consults
$20,000
Monthly medications
$12,000
24/7 concierge health support
$5,600
4x at home blood draws with mobile phlebotomist
$1,000
Dutch kits and analysis
$1000
Nutrigenomics and foundational biology report
$400
Total
$40,000
$250/month
Frequently asked questions
What is HRT?
Hormone replacement therapy (HRT) helps balance estrogen, progesterone and testosterone levels that drop with age. It relieves menopause symptoms and lowers the risk of long-term health issues caused by hormone changes.
How is it possible for this program to be so affordable at just $250 per month?
We’ve made healthcare simple and efficient. By using advanced lab testing and cutting-edge technology, we cut out expensive in-person visits and extra costs. This allows us to provide top-quality care at a price that works for more women.
Is HRT safe?
Your safety comes first. Our doctors carefully review your medical history to make sure HRT is right for you. For most women, HRT is safe and highly effective. Our team will explain any risks and benefits so you can feel confident.
How long does it take to see results?
Everyone’s different, but many women see improvements in hot flashes, night sweats, and sleep within a few weeks. Weight changes or muscle gain can take up to three months, with 80% of women feeling full relief by then. Your doctor will adjust your plan as needed.
I’m already taking supplements—will this conflict with those?
No worries. Our program works with your current supplements. Our team will check to make sure everything is safe and works together so you can stick to your routine.
Where are the physicians and the rest of the team located?
Our entire team—including doctors and customer care—is based in the US. You’ll have 24/7 support from people who understand your needs and are here to help anytime.
What kind of treatments do you offer?
Our program offers medications like estradiol, estriol, progesterone and testosterone (if recommended by your care team). They come in pills, creams or patches based on what works best for you. You’ll also get a custom supplement plan based on your needs, with options to buy trusted brands or a custom blend for an extra fee.
Is this program covered by insurance?
Not yet, but we offer flexible pricing and payment plans to keep it affordable for you.