Methylcobalamin is one of the active forms of Vitamin B12, an essential nutrient that plays a critical role in many bodily functions due to its role in various metabolic processes.

Energy Production: Vitamin B12 is essential for converting food into glucose, which the body uses for energy. Mood Regulation and Brain Health: B12 contributes to the synthesis of neurotransmitters that support brain health. Nerve Health, by supporting the maintenance of the protective layer around nerves Red Blood Cell production, preventing anemia DNA Synthesis and repair, working closely with folate (vitamin B9) in the synthesis of DNA and RNA- essential for the growth and function of all cells in the body. (See references below)

Research has demonstrated intramuscular B12 injections to be superior to B12 capsules or sublingual droppers. Furthermore, many individuals carry SNPs that significantly limit the oral and cellular absorption of B12, making IM injections the most ideal route of administration.

Cyanocobalamin has a cyanide on the vitamin instead of a methyl group. Simply put, it is inactive and can even be detrimental. Though we can activate a small proportion of it, it can actually replace natural stores of B12 with inactive B12, though it will show on blood labs as if it has normalized B12 levels.

Absolutely, administering both injections on the same day is generally safe. However, for those new to this, it might be wise to alternate days for each injection initially to monitor your body’s reaction.

Depending on dosage, some people feel immediate and drastic results- the moment the B12 begins infusing, you might feel a veil lifting alongside instant clarity. Others need a couple of weeks for results to kick in.

Intramuscular B12 injections can help those experiencing fatigue, sleep, mood or energy issues, as well as anxiety. They work by supporting the body’s methylation pathways. On a molecular level, methylation is a process by which a methyl group (CH3) is added to a molecule, often DNA, affecting gene expression and cell function. It’s an elemental biochemical reaction involved in many cellular processes across multiple biological pathways in the body- each shaping different aspects of our health. Methylation can profoundly impact the production and regulation of neurotransmitters, which play critical roles in mood, cognition, and overall brain function. Impaired methylation can lead to inefficient detoxification, with implications such as oxidative stress or inflammation. It also has a profound impact on fat metabolism through its regulation of gene expression, as well as its influence on enzymes that process fats in their synthesis, breakdown, and storage. Why methylcobalamin over cyanocobalamin or B12 capsules? Cyanocobalamin has a cyanide on the vitamin instead of a methyl group. Simply put, it is inactive and can even be detrimental. Though we can activate a small proportion of it, it can actually replace natural stores of B12 with inactive B12, though it will show on blood labs as if it has normalized B12 levels. Research has demonstrated intramuscular B12 injections to be superior to B12 capsules or sublingual droppers. Furthermore, many individuals carry SNPs that significantly limit the oral and cellular absorption of B12, making IM injections the most ideal route of administration.