Methyl-Guard Plus

2 Capsules, Once Daily | 45 Day Supply

Methylation is key to keeping homocysteine levels in check, as well as for facilitating multiple biochemical processes involving neurotransmitter synthesis, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance.

 

Maintaining a desirable level of homocysteine in the blood has joined healthy cholesterol and triglyceride levels as leading biomarkers for the maintenance of good cardiovascular health.* Preventing an undesirable homocysteine level is also associated with the maintenance of bone, female reproductive, cognitive, and neurological health.* 

 

Methyl-Guard Plus supports methylation and promotes healthy homocysteine levels with betaine (trimethylglycine), 5-MTHF (the active form of folate), riboflavin 5'-phosphate (the active form of vitamin B2), pyridoxal 5'-phosphate (the active form of vitamin B6), and methylcobalamin (an active form of vitamin B12).*

Benefits

92% Impact
Nutritional support for individuals who have MTHFR gene mutations
Enhanced cellular energy production fights fatigue
Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health
Promotes fat metabolism and lean body composition
Supports neurotransmitter production

Bones Brain Brain Nutrients Energy Hypomethylation Mood PCOS Women’s Health
  • Supports Healthy Methylation

    Methylation is a critical biochemical process in the body that affects DNA synthesis and repair, neurotransmitter production, and detoxification. Methyl-Guard Plus provides key nutrients like methylated folate, vitamin B6, and B12, which are essential for efficient methylation.
  • Promotes Cardiovascular Health

    Homocysteine is an amino acid that, at high levels, is associated with an increased risk of cardiovascular diseases. Methyl-Guard Plus helps maintain healthy homocysteine levels through the inclusion of folate, vitamin B6, and B12, which are involved in its metabolism.
  • Supports Brain Health

    The nutrients in Methyl-Guard Plus, such as methylated folate and vitamin B12, play a vital role in neurotransmitter production and brain function. This support can enhance cognitive function and emotional well-being, making it beneficial for overall mental health.

Ingredients & Dietary Information

Ingredients

Active
per day
%DRV*
Riboflavin 5'-Phosphate Sodium
90 mg
6923%
Pyridoxal 5'-Phosphate)
45 mg
2647%
Folate
5 mg DFE
1250%
Methylcobalamin
3 mg
125000%
Betaine Anhydrous (Trimethylglycine)
1.8 g
-

*Dietary Reference Values

Dietary Information

Gluten-free
Dairy-free
Soy-free

Notable Research Papers

B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients. 2016 Jan 27;8(2):68. doi: 10.3390/nu8020068. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/

Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. J Alzheimers Dis. 2020;77(2):781-794. https://pubmed.ncbi.nlm.nih.gov/32773392/

DNA methylation and its basic function. Neuropsychopharmacology. 2013 Jan;38(1):23-38. doi: 10.1038/npp.2012.112. Epub 2012 Jul 11. PMID: 22781841; PMCID: PMC3521964. https://pubmed.ncbi.nlm.nih.gov/22781841/

Methyl-Guard Plus FAQ

What is Methyl-Guard Plus?
Methyl-Guard Plus is a dietary supplement by Thorne that supports healthy methylation processes in the body, which are vital for DNA synthesis and repair, neurotransmitter production, and detoxification.
How do I take Methyl-Guard Plus?
The recommended dosage for Methyl-Guard Plus is typically one to two capsules daily, or as directed by a healthcare practitioner. It's best taken with meals.
Can Methyl-Guard Plus help with homocysteine levels?
Yes, Methyl-Guard Plus is specifically formulated to help maintain healthy homocysteine levels, which can reduce the risk of cardiovascular diseases.
Is Methyl-Guard Plus safe for long-term use?
Methyl-Guard Plus is generally safe for long-term use when taken as directed. However, it's always best to consult with a healthcare practitioner before starting any new supplement regimen.
Are there any side effects associated with Methyl-Guard Plus?
Most people tolerate Methyl-Guard Plus well. However, some individuals may experience mild side effects such as digestive discomfort. If you experience any adverse reactions, discontinue use and consult your healthcare practitioner.